• Skip to main content
  • Skip to secondary menu
  • Skip to primary sidebar

Indy Sports News

Indy Sports News

  • Colts
  • Basketball
    • Fever
    • Pacers
  • Colleges
    • Ball State
    • Butler
    • Indiana
    • Indiana State
    • Marian

Jaguars vs Colts Predictions

December 6, 2025 by Last Word On Pro Football

The Jaguars vs Colts Week 5 AFC South clash features two of the more interested teams in the league. Indianapolis sophomore quarterback Anthony Richardson has struggled to establish himself as a consistent passer through the beginning of the season. While their rushing attack, led by Pro-Bowler Jonathan Taylor, is strong, their passing game is a roller coaster.

Meanwhile, the Jaguars have been one of the league’s most disappointing franchises. Despite having a solid quarterback in former #1 overall pick Trevor Lawrence, Jacksonville is the NFL’s last remaining team without a win.

Jaguars vs Colts Odds

  • Moneyline: Colts (+125) vs Jaguars (-150)
  • Spread: Colts +3.0 (-120) vs Jaguars -3.0 (+100)
  • Over/Under: Over 46.0 (-110) / Under 46.0 (-110)

Jaguars vs Colts Prediction

Jags 17, Colts 21

The Colts face a clear level of uncertainty due to injury concerns. Both of their dual-headed rushing attack, Richardson (oblique) and Taylor (ankle) are listed as questionable. While losing either would drastically affect this games outcome, veteran Joe Flacco provided stability to the offense last week.

If either Richardson or Taylor can play, the rushing attack will remain dangerous. If Richardson misses, the combo of Flacco and Taylor will bring an unusual well-roundedness to Indy’s offense. Fifth-year running back Trey Sermon would likely handle lead back duties in a pass-heavy offense if Taylor were to be ruled out.

The Jags are dealing with their fair share of offensive injuries, lead rusher Travis Etienne Jr. and tight end Evan Ingram are both listed as questionable. However, Jacksonville has been a complete mess this season, even at their healthiest point.

On top of that, Jags head coach Doug Pederson appears to be frustrated and on super thin ice. Jacksonville will eventually find a way to turn things around under Lawrence. But it highly questionable whether the franchise gets back on track this week.

Expect Indy to end their nine-year loosing streak when matching up with the Jaguars in Jacksonville.

Jaguars vs Colts Best Bets

Jonathan Taylor First Touchdown Scored (+450)

Be sure to check the injury report before locking in this bet. If Taylor plays, he is the safest option to find the end zone. Richardson’s potential absence may actually open up more goal line carries than normal. But either way, the Colts offense begins and ends with thier star running back’s ability to produce.

Taylor has already posted four rushing touchdowns in as many contests. He is a solid bet to hit pay dirt again this week.

Evan Ingram 1st Half Touchdown Scored (+500)

Again, be sure to check the injury report here. Last season, Ingram’s 114 receptions became the second most a tight end has ever recorded in a single season. He was also projected for big production in 2024.

So far this year, he has been limited to one game, one reception, and five total receiving yards through four weeks.

Ingram and Lawrence have good chemistry and a sky high ceiling. If Ingram has recovered from his hamstring injury, expect Lawrence to use his red zone weapon early and often as the Jaguars offense attempts to find their footing.

The post Jaguars vs Colts Predictions appeared first on Last Word on NFL.

Filed Under: Colts

Primary Sidebar

Recent Posts

  • Sideline to Sideline: Off the field
  • Keys to the Game: Colts at Jaguars
  • Colts’ Daniel Jones out with right Achilles injury
  • Colts announce 7 inactive players for Week 14 game vs. Jacksonville Jaguars
  • Daniel Jones sustains Achilles injury in first quarter of Colts' Week 14 game vs. Jaguars, will not return

Categories

Archives

Our Partners

All Sports

  • Indianapolis Star
  • WTTV - CBS 4
  • 247 Sports
  • Bleacher Report
  • Ink On Indy
  • The Sports Fan Journal
  • The Spun
  • USA Today

Basketball

  • NBA.com
  • WNBA.com - Indiana Fever
  • 8 Points 9 Seconds
  • Amico Hoops
  • Basketball Insiders
  • High Post Hoops
  • Hoops Hype
  • Hoops Rumors
  • Indy Cornrows
  • Last Word On Pro Basketball
  • Pro Basketball Talk
  • Real GM

Football

  • Indianapolis Colts
  • Colts Wire
  • Horseshoe Heroes
  • Last Word On Pro Football
  • NFL Trade Rumors
  • Our Turf Football
  • Pro Football Rumors
  • Pro Football Talk
  • Stampede Blue
  • Total Colts

College

  • Big East Coast Bias
  • Busting Brackets
  • College Football News
  • College Sports Madness
  • Forgotten 5
  • Hammer And Rails
  • Hoosier Sports Report
  • Hoosier State Of Mind
  • Inside The Irish
  • Last Word On College Football - Notre Damee
  • One Foot Down
  • Punt John Punt
  • Saturday Blitz
  • Slap The Sign
  • The Crimson Quarry
  • Zags Blog

Copyright © 2025 · Magazine Pro on Genesis Framework · WordPress · Log in